Lasix was initially synthesized as a medicine to treat edema caused by different factors, including liver and kidney disorders and heart failures, and was approved by FDA as a diuretic in 1966. However, this medicine is also widely used for hypertension treatment because of its ability to decrease arterial blood pressure.
Furosemide, the active ingredient of Lasix, blocks re-absorption of sodium and chloride ions both in tubules (proximal and distal) and in the loop of Henle. Hypotension action of Lasix is achieved through distal vessels distention and diuretic effect.
Peculiarities of Usage
If your doctor prescribes Lasix to cure hypertension, it may be advised to take alone or in a combination with other drugs, depending on your tests, age and state of your health. According to the World Health Organization data, it’s not recommended to use Lasix and its generics containing furosemide to treat high arterial blood pressure in elderly patients, as there are cases of cardiovascular accident caused by taking furosemide by the representatives of this age group.
As for dosage, it’s usually advised to take 40 mg pill once or twice a day orally. Sometimes the dosage is increased to 160 mg a day, depending on the condition of a patient. The maximum possible dose of Lasix is 600 mg a day within several doses. Also, it’s better to avoid taking the drug less than 4 hours before your bedtime, as urination would interfere with your sleep. The best interval among doses is 6-8 hours.
If taking Lasix orally is impossible or reasonless, it may be prescribed intravascular or intramuscular. Then usual dosage for patients with hypertension will be 10-20 mg once or twice a day. If compared with Lasix taken orally, the dosage is much lower – it’s explained by the fact that the period of time for pills to start acting is 30-50 minutes, while injected Lasix has got a much more sudden action – in 15-20 minutes. In case of hypertension stroke the maximal intravascular dose of 200 mg is possible.
Reasons to Avoid Lasix
Although, the drug is quite effective, there are patients who can’t use it. The reasons to exclude treatment with Lasix are the following:
- hypersensitivity or allergy to its components;
- acute glomerulonephritis;
- kidney disease;
- cirrhosiss or other liver disease;
- electrolyte imbalance (hypokalemia, hyponatremia);
- water-salt imbalance.
Moreover, Lasix may lead to some side effects. It’s necessary to stop taking it and get medical help at once if you experience the following serious side effects:
- weight loss;
- stomach pain;
- nausea or vomiting;
- hearing problems;
- dark urine.
Lasix is, first of all, a diuretic medicine, so patients who use it to treat hypertension must be careful to avoid dehydration and extensive loss of salts and minerals. In general, side effects are rarely experienced, and the good effect prevails. Nevertheless, it’s strongly recommended to consult your doctor every time you feel uncomfortable while using Lasix and strictly follow the instructions to avoid possible undesired effects and achieve the result as soon as possible.